Today, I'm pleased to host author and friend, Bethany Macmanus. She's guest blogging on what diseases can be discovered through genetic analysis.
Bethany has graciously agreed to award one e-book copy of Nerve to a commenter of this posts. Comments close on Wednesday, March 25th.
Bethany has graciously agreed to award one e-book copy of Nerve to a commenter of this posts. Comments close on Wednesday, March 25th.
Welcome, Bethany!
I've
always found the ancient “nature vs. nurture” debate interesting, to the point
of writing a paper on it for my Child Growth and Development class in college.
What determines a person's physical traits, IQ, personality, or even their
ability to process things like gluten and phenylalanine? Is it mostly their
environment, or is it mostly their genes?
I've
heard of individuals who live the most healthy life they think possible, by
exercising regularly, eating what they've been told is most nutritious and
balanced, and seeing their physician for recommended appointments. When they
wake up one day and find out they have advanced cancer, they wonder what in the
world happened. Their environment, though it couldn't be controlled completely,
had been “nurtured” as much as possible. What, then, did their genes contribute
to the equation?
The
answer is, probably a lot.
Geneticists
are discovering more and more factors which are predetermined by what is written
on our DNA. Here is only a partial list, which I've taken from www.geneplanet.com:
·
Episodic
memory (KIBRA gene)
·
Pain
sensitivity (SCN9A gene)
·
Norovirus
resistance (FUT2 gene)
·
Bitter
taste perception (TAS2R32 gene)
You may
have heard of the double mastectomy actress Angelina Jolie underwent in 2013 to
prevent breast cancer. Genetic analysis showed she had a specific BRCA1
gene mutation, which is reported to make her 87% likely to test positive
for the disease. The BRCA1 and 2 genes are responsible for tumor suppression.
I
wondered what other disease processes can be tested through genetic analysis.
Gene Planet has a long list: Alzheimer's disease, asthma, atrial fibrillation,
breast cancer, celiac disease, colorectal cancer, gallstones, glaucoma, heart
attack, hypertension, lung cancer, MS, prostate cancer, psoriasis, rheumatoid
arthritis, diabetes (type 1 and type 2), restless leg syndrome, and venous
thromboembolism (a blood clot in an extremity).
The
list included a lot of the diseases with high mortality rates, which made me
have another thought. If I had one or all of these (very expensive) analyses
done, I sure wouldn't want this genetic information falling into the wrong
hands!
And so
I asked one of the story questions in my novel, Nerve:
What if a sample of my DNA was stolen from me and analyzed without my knowledge
or consent? What might the thief do with their new power over me? Find out when
you read!
************************************************************************
Bethany Macmanus lives in Houston with her husband, daughter, and son. After
practicing as an RN for five years, Bethany left the nursing field to pursue a
writing passion the Lord planted in her heart when she was a child. Nancy Drew
mysteries were her guilty pleasure during those early years, so she naturally
gravitates her pen toward the things that go bump in the night, and most of her
plots have a psychological spin. She’s allergic to cheese, Sulfa drugs, and
people who stop in the middle of intersections while driving.
Thanks for hosting me, Jordyn! I tried to be slightly cryptic...can't give away too much of the plot. I hope the post was informative to all. I'm looking forward to readers' comments. :)
ReplyDeleteThis sounds really interesting! I love reading Christian fiction. Thanks to Jordyn Redwood, I have taken to medical thrillers. Is this going to be a stand~ a~ lone or part of series? Amy Gribowskas
ReplyDeleteAmy, thanks for your comment! Yay, I'm so glad it has peaked your interest. For now, it's a stand-alone, but there are two characters who might speak to me and tell me their story, for a future book! I generally don't plot books in series, but so far, my other two books have had characters who want their stories told. I have learned to just wait on the characters. LOL!
ReplyDeleteAs a retired nurse I love reading books from the medical genre. Looking forward to reading your book. I'm a fan/reviewer for Jordyn Redwood. Love her books!
ReplyDeleteHi, Mattie! Yes, I've seen your comments many times, both on Jordyn's FB and blog. I didn't know you are a retired nurse. Hooray for nurses!! :) It's great to be on the receiving end of your comments, this time. Blessings!
ReplyDeleteI love, love, love medical thrillers! Please enter me to win an e copy of this book, please.
ReplyDeleteI always love to hear about new medical thrillers too, Susan! Thanks for your comment.
ReplyDeleteAs a nurse, I love medical thrillers.
ReplyDeleteSounds a fascinating read.
ReplyDeleteHello, Ruth. Thanks for your comment! Seems like we've got a lot of nurses here. :-)
ReplyDeleteDiana, thanks for stopping by!
ReplyDelete